Circadian Rhythm of Neuron R15 of Aplysia californica: In Vivo Photoentrainment

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Circadian Rhythm of Neuron R15 of Aplysia californica: In Vivo Photoentrainment.

(1) The neuron R15 in the parietovisceral ganglion of Aplysia has a circadian rhythm of spiking activity when recorded in the isolated ganglion. The rhythm is entrained in vivo by light-dark cycles. (2) The phase of the R15 rhythm is a function not only of the entraining light schedule, but also of the time of dissection. Changes in the dissection time during the light portion of the light-dark...

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Purification and sequencing of neuropeptides contained in neuron R15 of Aplysia californica.

R15 is a large identified neuron present in the abdominal ganglion of the mollusc Aplysia. Previous studies have indicated that this neuron may play a role in water balance and possibly renovascular functions. A peptidic factor contained in the neuron R15 has been shown to increase the water content of Aplysia. To determine the structure of the peptides contained in R15, we purified the extract...

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Decreased Response to Acetylcholine during Aging of Aplysia Neuron R15

How aging affects the communication between neurons is poorly understood. To address this question, we have studied the electrophysiological properties of identified neuron R15 of the marine mollusk Aplysia californica. R15 is a bursting neuron in the abdominal ganglia of the central nervous system and is implicated in reproduction, water balance, and heart function. Exposure to acetylcholine (...

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Neuron-specific membrane glycoproteins promoting neurite fasciculation in Aplysia californica

We have generated a library of mouse monoclonal antibodies against membrane proteins of the nervous system of the marine snail Aplysia californica. Two of these antibodies, 4E8 and 3D9, recognize a group of membrane glycoproteins with molecular masses of 100-150 kD. We have called these proteins ap100, from the molecular mass of the most abundant species. Based on Western blots, these proteins ...

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Synaptic actions of identified peptidergic neuron R15 in Aplysia. I. Activation of respiratory pumping.

The purpose of the study described in this and the following two companion papers was to determine the synaptic actions of neuron R15, an endogenously bursting neurosecretory cell in Aplysia, as a step toward determining its physiological function. The results described in this paper demonstrate that activity in R15 increases the frequency of bursting in the R25/L25 network that triggers respir...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1975

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.72.6.2408